Lab of Combinatorial Genetics & Synthetic Biology @ HKU
News
Dr Wong gave a talk in the A+ outreach event to secondary school students about CRISPR genome editing.
event link
The acticle Accurate top protein variant discovery via low-N pick-and-validate machine learning is now available online.
Article link
Congrats to Athena, John, Nick and Fred!
BOCHK Science and Technology Innovation Price award ceremony
Congrats to Dr. Wong as the awardee of the BOCHK Science and Technology Innovation Price 2023.
Event details
Lab retreat 2023.
The article Discovery of regulatory motifs in 5′ untranslated regions using interpretable multi-task learning models is now available online.
Congratulations to Weizhong and John!
The article High-throughput screening of genetic and cellular drivers of syncytium formation induced by the spike protein of SARS-CoV-2. is now online!
Congratulations to Charles and Bei!
article link
Nature portfolio blog post
Lab visit from the Hong Kong Laureates Forum.
Hong Kong Laureates Forum is an academic exchange event to connect current scientist and young scientists in Hong Kong and around the world in various disciplines in science and technology.
Dr Wong talks about applying AI on CRISPR engineering in the news.
News article published in AM730:
Lucas has been awarded the Mr & Mrs SH Wong Foundation Scholarship for MRes[Med] 2023-24.
Well done Lucas!
Lucas has been granted the Research Internship Award under the Undergraduate Research Fellowship Programme (URFP)
Well done Lucas!
HKU Biomedical Sciences Summer Academy 2023
Many thanks to our lab tour guides John, Bei and Charmaine, and others helping out in the event. It was a collective effort to engage 35 students, as well as their teachers, from 7 different local secondary schools in this research experience.
A day @ BME
Many thanks to our lab tour guides John, Charles, Bei and Jessie at the A day @ BME event!
The Base-editors profiling platform developed by John is reported in local news outlets.
News coverage: 香港大學開發全球首個篩選精確基因編輯工具平台 in TVB news, 信報, 大公報, 文匯報, 東方日報, Labiotech, Phys.org, finance.sina.com.cn, 中国新闻网 etc.
HKU press info
Wenweipo
John’s review Advancing CRISPR/Cas gene editing with machine learning is avaialble online.
Congratulations to John!
link
John’s paper Parallel engineering and activity profiling of a base editor system is avaialble online.
Congratulations to John!
link
Dr. Wong talked about the use of CRISPR in biomedicine in the Sci-Fi-Sci 2023 festival.
Sci-Fi-Sci is co-organised by the Hong Kong Science Museum, the Hong Kong Space Museum and the Film Programmes Office.
Programe info
CombiSEAL featured in HKU digital art Optimizing the Future by Nick Teeple.
HKUMed launched the exhibition Medicine and Healthcare Through the Lens of Digital Art to celebrate its 135th anniversary.
Among the digital art pieces on display, CombiSEAL is featured in Optimizing the Future by Nick Teeple.
link
What are the current bottlenecks in developing and applying CRISPR technologies?
The current prospective on CRISPR technology is now available online.
link
Oliver’s graduation
Well done Oliver and all the best!
The SaCas9 optimization paper has received quite a bit of media coverage.
HK01.com
Sing Tao Daily
news-medical.net
article link
Bei’s review CRISPR screening in cancer stem cells is available online.
Well done Bei!
Review link
Official Launch of InnoHK.
Dr Wong attended the official InnoHK launch ceremony.
Dawn and Athena’s work on SaCas9 optimization is now published in Nature Communications.
Congrats to Dawn and Athena! Here is a featured blog post of the article:
Engineering CRISPR-Cas9 proteins en masse with much less experiments
The highly accurate SaCas9 variants are featured covered in local News.
Ta Kung Pao news
Congrats to Zero and the team! The related article is published in Nucleic Acids Research.
The highly accurate SaCas9 variants are featured in HKUMed News!
News link
Congrats to Zero and the team! The related article is published in Nucleic Acids Research.
The lab’s finding on Combinatorial drug treatment for liver cancers is covered by local newspapers.
Headline Daily
Sing Tao Daily
Hong Kong Economic Journal
Well done, team!
AW lab’s Christmas lunch.
The lab visited Hotel W for a nice buffet with a splendid view of the Victoria harbour. Congrats to Oliver, Yuan, Bei, Becky and John for winning the lucky draw.
Xu Feng’s paper is available online.
Well done!
John has received the Hong Kong PhD Fellowship (HKPF) and HKU Presidential PhD Scholarship (HKU-PS).
Superb achievement, John! Have fun for your PhD!
Our first day in InnoHK!
Very excited to start many new projects! Many Thanks to the Centre for Oncology and Immunology Limited for hosting us!
Visting the Centre for Oncology and Immunology Limited in Science Park!
Great facilities. And an interestingg visit in InnoCell
Becky has received the HKU University Postgraduate Fellowships (UPF).
Congrats, Becky! Great start of the PhD journey!
Happy BME lab tour day!
Thanks everyone, for helping out. Hope you had a great time with the visitors!
Goodbye Dawn and Cindy
Wish you all the best!!!
William has graduated!
Congratulations to William!
CombiPIPE protocol published in STAR Protocols
Well done on the excellent protocol and the development of CombiPIPE. Congrats to Nick, Yukkei, Becky and Gigi!
protocol link
Dr. Wong was interviewed in Sing Tao Daily on the development of CRISPR-Cas9 technology
news link in SBMS webpage
YukKei and Gigi have published a book chapter “High-Throughput Protein Engineering by Massively Parallel Combinatorial Mutagenesis” in Strucutral Genomics.
Congratulations to Yukkei and Gigi!
book chapter link
Dr. Wong was invited to talk on “Second-generation combinatorial genetics technologies for therapeutic target discovery and protein engineering” at Department of Chemical Pathology of the Chinese University of Hong Kong via Zoom.
Dr Wong has won the NSFC Excellent Young Scientists Fund 2020.
Congratulations to Dr Wong!
Charles has been awarded with the HKU University Postgraduate Fellowships (UPF)
Congratulations to Charles!
Gigi, Nick, Zero, Becky, Xu Feng, Dawn, and Dr. Wong for the Faculty Outstanding Research Output Award 2020, HKUMed
Congratulations to all the awardees!
The lab’s second paper published on Cell Reports!
Congrats to Nick, Becky, Yukkei, Zero, Gigi, Cindy, Sophia, Jieran and Jien Vei! All the hard work finally pays off!
Lab Visit for Secondary School Students
Becky has received her Mphil degree and John has received his BBiomedSc degree!
Warmest congratulations on your achievement!
Invited talk at the Workshop on Enzyme Evolution for Advanced Biotechnology
Dr. Wong was invited to talk at the Workshop on Enzyme Evolution for Advanced Biotechnology in Shanghai!
Invited talk at the 9th CUHK International Symposium on Stem Cell Biology & Regenerative Medicine
Dr. Wong was invited to talk at the 9th CUHK International Symposium on Stem Cell Biology & Regenerative Medicine.
Dr. Wong was invited to talk at NEB’s NGS Symposium.
Dr. Wong was invited as a keynote speaker in YASHK’s Talk Series
Dr. Wong was invited as a keynote speaker in the Talk Series on Emerging Technologies - Science, Opportunities and Challenges: Nature’s Red Pencil: Writing and Rewriting Genomes organized by the Hong Kong Young Academy of Science.
Bye Jessie, Rachel, and Daniel
Good luck Jessie, Rachel, and Daniel moving onto their next steps!
Becky at the SEED conference 2019
Becky attended the 2019 Synthetic Biology: Engineering, Evolution & Design (SEED) conference in New York City!
The lab’s first paper got accepted by Nature Methods!
AW lab’s Disney Retreat
Invited talk at Karolinska Institutet, Sweden
Dr. Wong is invited to give a talk at Karolinska Institute in Stockholm, Sweden.
Jessie got awarded at the HKU Research Colloquium for Science Undergraduate Students
Congratulations to Jessie on being awarded one of the best poster presentations in the HKU Research Colloquium for Science Undergraduate Students 2018-2019! Well done!
AACR 2019 Meeting
Nick and William went to the AACR 2019 Meeting in Atlanta, GA.
Invited lecture @ SBMS Research Day 2018
Dr. Wong was invited to give a lecture during the School of Biomedical Science Research Day.
Lab lunch
The lab got lunch at Japas in Kennedy Town.
Invited talk at TRS symposium
Dr. Wong was invited to give a talk at the TRS symposium: Gastric Cancer Genomics and Beyond: Organoids, Genomics and Cell Biology.
Croucher Summer Course in Precision Genome Engineering by CRISPR
Exciting to have the Croucher Summer Course In Precision Genome Engineering by CRISPR in Hong Kong!
Invited talk at the 5th Macau Symposium on Biomedical Science
Dr. Wong was invited to give a talk at the 5th Macau Symposium on Biomedical Science.
Jessie awarded the HKU Undergraduate Research Fellowship
Congratulations to Jessie on being awarded the HKU Undergraduate Research Fellowship!
Invited talk at MWLC Scientific Symposium 2018
Dr. Wong was invited to give a talk at the MWLC Scientific Symposium 2018 held by Karolinska Institutet, HK
Invited talk at Department of Chemical Pathology, CUHK
Dr. Wong was invited to give a talk at Department of Chemical Pathology, CUHK.
Invited talk at City University of Hong Kong
Dr. Wong was invited to give a talk at City University of Hong Kong.
The first international symposium organized by our lab
Engineering Complex Genetic System is the first international symposium organized by our lab! Thanks Christy for designing the conference posters and banners, and all lab members for helping to organize this exciting event!
Invited talk at DIY Bio
Dr. Wong was invited to give a talk at DIY Bio.
Invited lecture at the 12th International Symposium on Healthy Aging
Dr. Wong was invited to give a lecture at the 12th International Symposium on Healthy Aging.
Invited lecture at Department of Pathology, HKU
Dr. Wong was invited to give a lecture at Department of Pathology, HKU.
Invited lecture at the Hong Kong Society for Developmental Biology
Dr. Wong was invited to give a lecture at the Hong Kong Society for Developmental Biology.
Invited lecture at SBMS Inaurgural Sympoisum 2016
Dr. Wong was invited to give a lecture at SBMS Inaurgural Sympoisum 2016.
